MySQL Enterprise Backup 4.1 Release Notes
MySQL Enterprise Backup 4.1 only supports MySQL 5.7. For MySQL 5.6 and earlier, use MySQL Enterprise Backup 3.12.
For MySQL 5.7.11 and earlier, backup for InnoDB tablespaces encrypted with “MySQL Enterprise Transparent Data Encryption (TDE)” is not supported by MySQL Enterprise Backup 4.1. See the discussion here for details.