MySQL Instance Manager is been deprecated in MySQL 5.1 and is removed in MySQL 5.5.
After you set up a password file for the MySQL Instance Manager and Instance Manager is running, you can connect to it. The MySQL client/server protocol is used to communicate with the Instance Manager. For example, you can connect to it using the standard mysql client program:
mysql --port=2273 --host=im.example.org --user=mysql --password
Instance Manager supports the version of the MySQL client/server protocol used by the client tools and libraries distributed with MySQL 4.1 or later, so other programs that use the MySQL C API also can connect to it.